Source-specific priming of lung NK cells by Pseudomonas LPS enhances resistance to bacterial pneumonia

Researchers have discovered key biomarkers that are strongly linked to all-cause mortality and identified four measurements with independent predictive power.

An important goal in the research community is to build a robust measure of biological age, the burden of age-related damage and dysfunction contributing to disease and mortality, that can be used to rapidly assess the quality of any potential intervention to…

Any sufficiently complex biological data that changes with age can be used to construct an aging clock. Here, researchers report on a clock derived from images of the nuclei of hematopoietic stem cells.

The antimicrobial drug K21 acts via disruption of bacterial membranes, but is also known to produce improved wound healing, which suggests the involvement of mechanisms other than antimicrobial activity.

This study looks at how the decline in chaperone-mediated autophagy in aging alters senescent cell properties leading to an impairment in their immune clearance.

Author Correction: Multilingualism protects against accelerated aging in cross-sectional and longitudinal analyses of 27 European countries

“[Pregnancy] It’s a cardiovascular stress test because the plasma volume expands so much. It is a metabolic stress test because there's increased insulin resistance.”‒ Katie Gray

As we grow older, our bodies accumulate "zombie cells"-living cells that have stopped dividing or functioning normally-but linger in our tissues, contributing to chronic inflammation and age-related diseases.

Findings suggest systemic environment affects biological age of transplanted hearts, with implications for improving organ allocation in transplantation.