The State of Development for Therapies to Treat Tauopathies

In a new study, thymic tissue implanted in the spleen improved immune responses against viruses and tumors and reversed age-related thymic involution in mice [1].

Alzheimer’s disease (AD) biomarkers may be associated with decline in non-cognitive domains of intrinsic capacity (IC), but such evidence has not been synthesized.

The research community is in the early stages of development of therapies for age-related neurodegeneration based on reprogramming the supporting glial cells of the brain to provoke transformation into neurons.

Atherosclerosis, the growth of fatty plaques in blood vessel walls, is the largest cause of human mortality.

Aging is associated with myeloid-biased hematopoiesis, which leads to the establishment of a pro-inflammatory microenvironment.

Exclusive: Prof Jim Al-Khalili says he will offer solution to ‘arrow of time’ problem in Royal Institution lectures Tech billionaires attempting to live for ever are, quite literally, wasting their time, a leading physicist has said.

The ability to initiate stepping promptly and accurately is critical for safe mobility in later life. Choice stepping reaction time (CSRT) is an independent predictor of recurrent falls in older adults and is often prolonged in dementia.

Scientists found that declining levels of the brain protein Menin may help drive aging, with lower levels in mice linked to inflammation, cognitive decline, weaker bones, and thinner skin.

Researchers developed 38 sex-specific biological aging clocks across 15 organ systems, finding differences between females and males in genetic architecture, molecular signatures, disease associations, and mortality patterns.