Clearing Damaged Mitochondria to Fight Skin Photoaging

Researchers publishing in Aging Cell have found that a cocktail of molecules released by human umbilical cord mesenchymal stem cells (hUC-MSCs) can mitigate sun-induced skin aging (photoaging) in mice by restoring their cells’ ability to get rid of their own damaged mitochondria…

Lifespan.io · 20:35

№02 / 19 · Fight Aging!

Lingering Senescent Cells in Aged Tissues Use PD-L2 to Evade Destruction by Immune Cells

PD-L1 and PD-L2 are components of immune checkpoints, widely expressed in tissues throughout the body.

Fight Aging! · 19:01

№03 / 19 · Fight Aging!

Calorie Restriction Slows the Accumulation of Nuclear DNA Damage

Damage to nuclear DNA occurs constantly, and near all of it is immediately repaired. A tiny fraction lingers, however, and over time a burden of mutational damage builds up in tissues throughout the body.

Fight Aging! · 11:22

№04 / 19 · Fight Aging!

Going Beyond Life Span and Health Span to Functional Spans Such as Movement Span

Sports medicine is somewhat focused on specific functional aspects of health, and so it was probably inevitable that factions in that community found the measures of life span and even health span to be lacking.

Fight Aging! · 11:11

№05 / 19 · Nature Ageing

Omaveloxolone functions as a molecular crowbar-like degrader of STING to alleviate aging-related inflammation

Nature Ageing · 01:00

№06 / 19 · Nature Ageing

How fast are you ageing? Ask AI

Nature Ageing · 01:00

№07 / 19 · ScienceAlert

Blood-Brain Barrier Successfully Repaired in Alzheimer's Models

ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.

ScienceAlert · 01:44

№08 / 19 · npj Aging

Validation and refinement of a biomarker panel for frailty assessment and prediction of muscle weakness in older adults

npj Aging · 01:00

№09 / 19 · npj Aging

Age-related changes in olfactory function: electrophysiological recordings from the olfactory mucosa and human brain

npj Aging · 01:00

№10 / 19 · npj Aging

Deciphering senescence-associated mechanisms through cell painting & transcriptomics

npj Aging · 01:00

№11 / 19 · npj Aging

Effects of a three-month exercise programme on cognition, mood and neurogenesis: the NeuroFit randomised controlled trial

npj Aging · 01:00

Also today · №12–19

№12 · npj Aging · 01:00

A composite frailty index enables quantification of functional aging and identification of gerotherapeutic drugs in the house cricket

A composite frailty index enables quantification of functional aging and identification of gerotherapeutic drugs in the…
№13 · ScienceAlert · 23:00

Two Remote Amazon Communities Have Strikingly Low Dementia Rates. Scientists Are Struggling to Understand Why.

ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a…
№14 · GeroScience · 01:00

Mediating role of depressive symptoms in the association between trajectories of instrumental activities of daily living and all-cause mortality in middle-aged or older adults: a cohort study in South Korea

The ability to independently perform instrumental activities of daily living (IADL) is important for the quality…
№15 · GeroScience · 01:00

Deep learning–derived retinal age gap and its associations with lifestyle, systemic, and ocular health in a health screening cohort

Individuals of the same chronological age differ in biological aging, and scalable, noninvasive markers are needed…
№16 · GeroScience · 01:00

Integration of methylome and transcriptome reveals age-associated signatures of stage-specific dynamics and regulatory remodeling in dogs

Aging in mammals is characterized by widespread yet coordinated epigenetic alterations. However, integrative analyses of DNA…
№17 · News-Medical · 20:02

Study highlights drop in harmful medication use among adults with cognitive disorders

Adults 65 and older with cognitive disorders such as dementia, are more likely to suffer negative…
№18 · News-Medical · 18:24

New funding boosts data archive that tracks healthy aging environments

With an $11 million award from the National Institute on Aging, University of Michigan researchers will…
№19 · News-Medical · 17:51

New indicators could accelerate development of anti-aging drugs

Twelve candidate indicators, based on studies in mice, could make developing anti-aging interventions faster-while offering new…

Edition №74 complete

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