The Most Powerful Economic Productivity Lever of All Time

A great deal of advocacy for the development of therapies to slow and reverse aging has moved on from a focus on reducing suffering.

Fight Aging! · 19:01

№02 / 16 · GeroScience

The TyrRS cascade: circadian gating of neuronal DNA repair and its collapse in aging

Age-related neurodegenerative diseases are characterized by progressive DNA damage in post-mitotic neurons against a backdrop of deteriorating circadian rhythms, yet the molecular link between these conjoined features of brain aging remains unclear.

GeroScience · 01:00

№03 / 16 · GeroScience

Age-dependent changes in lipid droplet distribution and vascularization in naked mole rat vs. mouse hippocampus

The accumulation of lipid droplets in microglia has been reported to increase in response to ageing and age-related diseases like Alzheimer’s disease.

GeroScience · 01:00

№04 / 16 · Fight Aging!

Impaired Lactate Metabolism in Liver and Muscle as an Important Cause of Sarcopenia

Sarcopenia is the name given to severe age-related loss of muscle mass and strength. This loss occurs steadily throughout later life.

Fight Aging! · 11:22

№05 / 16 · Fight Aging!

Oxidation of SOD1 in Skin Aging

Normal cell metabolism, particularly the activities of mitochondria, generates oxidizing molecules that react with proteins to disrupt their function. This damage occurs constantly, and is repaired constantly.

Fight Aging! · 11:12

№06 / 16 · Nature Aging

Publisher Correction: Three-dimensional mapping of intact ovaries reveals the aging dynamics of the ovarian reserve

Nature Aging · 01:00

№07 / 16 · ScienceDaily Aging

Scientists find an immune “false alarm” that may drive rapid aging

Scientists have discovered that some severe genetic disorders linked to rapid aging may be driven not just by damaged DNA, but by the body’s overreaction to that damage.

ScienceDaily Aging · 15:05

№08 / 16 · Nature Ageing

Map of brain ‘microproteins’ could offer new clues to Alzheimer’s disease

Nature Ageing · 01:00

№09 / 16 · ScienceAlert

Common Gum Problem Is Linked to a 61% Higher Alzheimer's Risk

ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a story, subscribe here.

ScienceAlert · 01:28

№10 / 16 · npj Aging

Associations of physical fitness with brain structure, pathology and cognition in cognitively normal older adults

npj Aging · 01:00

№11 / 16 · npj Aging

When nights are no longer dark: Aging and light pollution reshape visual system rhythms

npj Aging · 01:00

Also today · №12–16

№12 · npj Aging · 01:00

Burden of cataract in the Western Pacific Region from 1990 to 2023: an analysis based on the Global Burden of Disease study

Burden of cataract in the Western Pacific Region from 1990 to 2023: an analysis based on…
№13 · npj Aging · 01:00

Permissive but not causative: layer-specific LHCGR alterations in ovarian aging

Permissive but not causative: layer-specific LHCGR alterations in ovarian aging
№14 · GeroScience · 01:00

Vitality capacity association with lifelong aerobic physical activity in older adults

The distinction between healthy and pathological ageing has led to the concept of vitality capacity, which…
№15 · GeroScience · 01:00

Retrotransposable element derepression distinguishes DNMT3A -mutant from TET2 -mutant clonal haematopoiesis

Clonal haematopoiesis (CH) is driven by somatic mutations in haematopoietic stem cells that generate clonal populations…
№16 · News-Medical · 14:30

Study: Multiple dietary patterns linked to slower biological aging

A study by DZNE finds that healthy eating is associated with slower biological aging-and that there…

Edition №73 complete

Return tomorrow.
Live longer.

Aggregated longevity news, not medical advice. Consult a clinician before acting on anything you read here.