Semaglutide to Reduce Calorie Intake Slows Aging in Female Mice, as Might be Expected

In a recent study, researchers have evaluated how responsive several DNA methylation (DNAm) biomarkers are to a range of longevity interventions [1]. Testing lifespan-extending interventions in humans has a major problem: it can take many years, or even decades, to see results.

Cerebral small vessel disease is a major contributor to stroke and cognitive decline and is characterized by white matter hyperintensities (WMH) and microstructural alterations detectable via diffusion-weighted imaging parameters, including free water (FW) and fractional anisotropy (FA).

Bioelectrical phase angle is an integrated marker of cellular integrity, fluid distribution, nutritional status, and physiological reserve, but its relationship with objective sensory function in later life remains unclear.

Past research has noted that socioeconomic status is a part of a web of correlations that include wealth, intelligence, education, lifestyle choices, and longevity.

Screening compound libraries for effects on aging in short-lived species has grown to become a significant area of interest in the aging research community.

3D culture reverses LNC replicative aging via FOSL1 upregulation, enhancing mitochondrial function and alleviating oxidative stress.

Cardiovascular disease is rapidly rising across ASEAN due to urbanization, ageing, and widespread risk factors, worsening health inequalities and economic burden.

Ferroptosis and ovarian senescence: integrating lipid metabolism, iron homeostasis, and established aging pathways

Rare cancer incidence and mortality trends among older adults in Martinique: a population-based registry study, 2008–2022

Copper and iron are redox-active micronutrients with tightly coupled homeostasis, yet how copper modulates iron-dependent stress responses remains unclear. Using Saccharomyces cerevisiae under nutrient-limited conditions, we uncoupled proliferative growth from long-term survival to dissect metal-dependent adaptation.