Immune System Signatures Correlate with the Near Term Risk of Developing Atherosclerosis

Naturally aged mice provide an important platform for studying frailty because functional decline emerges during biological aging rather than through acute injury or artificial manipulation.

Oligodendrocytes resident in the brain are responsible for maintaining the insulating myelin sheaths around axons that are required for the effective transmission of electrical impulses between neurons.

Blood tests to assess Alzheimer's disease risk and progression exist, for example based on the presence of circulating varieties of tau protein, but there is a great deal of room for improvement.

Thigh muscle fat infiltration (TMFI), estimated from MRI, is associated with increased mortality and diseases affecting multiple organ systems and mediates the effects of lifestyle factors on health. Multi-omics analyses delineate the genetic, cellular, transcriptional, proteomic, and metabolic architecture of TMFI.

A study of people over 90 found that dementia risk remains strongly shaped by sex, race and genetics, with women and black participants facing notably higher risks.

The disease burden and risk factors of age-related diseases in Southeast Asia, East Asia, and Oceania: an analysis of the Global Burden of Disease Study 2023

Novel Wasserstein distance-based sleep-activity regularity metrics from wearable data for healthy aging: J-HAS

Although motor and cognitive functions are closely interconnected in daily life, they are typically assessed separately in fall assessments.

Groundbreaking study published in Alzheimer's & Dementia reveals the crucial links between the NAD⁺-mitophagy axis and neurodegeneration.