A major Alzheimer’s risk gene may shrink brain cells years before symptoms

Single-cell immune profiling found that CD4 cytotoxic T lymphocytes become more abundant around age 100, showing stepwise differentiation and substantial clonal expansion.

Older adults with mild cognitive impairment and sleep problems who took at least 5,000 IU of vitamin D daily scored more than 13% higher on a cognitive test than those taking none.

Greenland sharks may live for 400 years without suffering the kind of retinal decline normally associated with aging. Researchers found healthy eye tissue and active proteins specially adapted for seeing blue light in the dim Arctic depths.

This study presents a network-based model to predict intracellular responses to shifts in the extracellular environment and demonstrates the utility of the framework by estimating chondrocyte responses to age-associated extracellular changes.

Reprogramming of Corticospinal Neurons Improves Recovery of Function in Mice Following Stroke Reviewing the Aging of the Gut Microbiome and Interventions Known to Improve Its Composition Mechanisms by Which Air Pollution Contributes to Parkinson's Disease RANKL Inhibition Slows Aging in Progeroid Mice