A Drug Combination Fights Both Senescence and Cancer

In Aging, the Conboys and their team have described how a combination treatment kills both senescent and cancer cells and lengthens the lives of old mice. Just as it does in mice, the incidence of cancer rises with age in people [1].

Lifespan.io · 21:53

№02 / 21 · Fight Aging!

Is it Reasonable to Say that Obesity Accelerates Aging?

In order to produce an airtight answer to the question of whether obesity accelerates aging, versus merely being very bad for one's health, one has to have an airtight definition of aging.

Fight Aging! · 19:33

№03 / 21 · Lifespan.io

Forever Healthy Launches the Evipedia Browser Extension

Staying informed about health and longevity interventions can be tedious and time-consuming.

Lifespan.io · 15:17

№04 / 21 · Fight Aging!

Targeting Senescent Cells to Treat Age-Related Chronic Pulmonary Disease

A sizable body of evidence points to a meaningful role for the accumulation of senescent cells in the onset and development of age-related pulmonary conditions such as idiopathic pulmonary fibrosis.

Fight Aging! · 11:22

№05 / 21 · Fight Aging!

Reviewing the State of Aging Clocks for the Brain

There are now scores of aging clocks in the literature, most of which have come and gone and see little adoption.

Fight Aging! · 11:11

№06 / 21 · Nature Aging

A National Institute on Aging workshop on sex differences in health across the lifespan

In December 2025, the Division of Aging Biology, National Institute on Aging (NIA) at the National Institutes of Health (NIH), in collaboration with staff from other NIA divisions, NIH institutes and the Veterans Health Administration, convened a workshop to explore the mechanistic…

Nature Aging · 01:00

№07 / 21 · Aging Cell

Distinct Transposable Element Transcript Patterns in Microglia Across Aging and Alzheimer's Disease

Microglia-specific transposable element patterns across human aging, Alzheimer's disease, mouse models of Alzheimer's disease pathology, and in vitro experiments.

Aging Cell · 05:10

№08 / 21 · Nature Ageing

From inflammaging to precision psychiatry: metabolic–immune crosstalk as a driver of late-life depression trajectories

Nature Ageing · 01:00

№09 / 21 · Nature Ageing

InsP3R signaling and actomyosin-dependent mitochondrial dynamics play essential roles in mitochondrial stress-induced longevity

Nature Ageing · 01:00

№10 / 21 · Nature Ageing

Decay of the Lef1-Srsf3-microRNA axis impairs DNA damage response and underlies stem cell aging

Nature Ageing · 01:00

№11 / 21 · npj Aging

Aging-induced hepatocyte CD44 drives IL6/STAT3 signaling that associates with impaired function of neighboring T cells

npj Aging · 01:00

Also today · №12–21

№12 · npj Aging · 01:00

Interpretable epigenetic clock links aging pathways and disease-specific methylation profiles

Interpretable epigenetic clock links aging pathways and disease-specific methylation profiles
№13 · npj Aging · 01:00

Sex-specific effects of parental age on the physiology of offspring in a long-lived seabird

Sex-specific effects of parental age on the physiology of offspring in a long-lived seabird
№14 · Aging Cell · 22:40

Featured Cover

Cover legend: The cover image is based on the article Podocyte mPGES-2 Determines Renal Aging and…
№15 · Nature Aging · 01:00

Three-dimensional mapping of intact ovaries reveals the aging dynamics of the ovarian reserve

The spatiotemporal dynamics of the depletion of the ovarian reserve remain incompletely understood.
№16 · Nature Aging · 01:00

Author Correction: Trained immunity links hematopoietic stem cell aging to aging-associated inflammation

Author Correction: Trained immunity links hematopoietic stem cell aging to aging-associated inflammation
№17 · News-Medical · 04:56

Your social life may leave a mark on how fast you age

Positive social experiences were associated with longer survival, while childhood adversity predicted shorter survival in a…
№18 · News-Medical · 04:42

Study sheds new light on the physiological roles of protein quality control at the ribosome

Scientists at the Center for Molecular Medicine Cologne (CMMC) and the CECAD Cluster of Excellence on…
№19 · npj Aging · 01:00

Nuclear aging in polyglutamine-induced neurodegeneration

npj Aging, Published online: 12 August 2026; doi:10.1038/s41514-026-00469-4 Nuclear aging in polyglutamine-induced neurodegeneration
№20 · npj Aging · 01:00

Hesperetin activates the Hmgcs2-Pparα-Cisd2 signaling axis and delays liver aging

Hesperetin activates the Hmgcs2-Pparα-Cisd2 signaling axis and delays liver aging
№21 · npj Aging · 01:00

Human in vitro skeletal muscle models recapitulate age-related atrophy and contractile decline induced by aged serum

Human in vitro skeletal muscle models recapitulate age-related atrophy and contractile decline induced by aged serum

Edition №39 complete

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