The Conservative View on the Current Peptide Craze

Sleep quality is well established to decline with age and age-related disease. A sizable medical and supporting industry is devoted to attempts to improve sleep quality via what are essentially compensatory approaches to intervention.

A useful side-effect of publishing under a copyleft license is that one can be lazy about formally publishing compilations of past material. Sooner or later someone else will get around to it.

This Perspective proposes a senotype framework for classifying senescent cells by their origins, molecular features and effects, which will foster comparison of diverse senescent states, including those with adaptive or maladaptive functions.

Nikolich et al. highlight immunoengineering approaches including advances in extracellular matrix and biomaterials, microphysiological and organoid systems, and tissue-targeted vaccine and drug delivery approaches, to improve our understanding of immune aging and inform translational strategies.

Mapping senescent cells across tissues, species and lifespan.

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Association of potentially inappropriate prescribing with frailty among older adults with multimorbidity in Northwest Ethiopia

Sensory impairment (SI) and accelerated epigenetic aging are both linked to later-life vulnerability, yet their joint value for risk stratification remains poorly understood.

Statin optimization in older adults is increasingly relevant within the geroscience framework of cardiovascular ageing. This randomized controlled trial evaluated whether pharmacist-led pharmaceutical care improves lipid outcomes and statin adherence in community-dwelling older adults receiving primary care.