Mitochondrial quality control in health and disease: mechanisms and therapeutic targets

Nature Ageing · 01:00

№02 / 20 · Fight Aging!

A Novel View of Age-Related Mitochondrial Dysfunction as a Failure of Adaptability

Every cell contains hundreds of mitochondria, the evolved descendants of what were once symbiotic bacteria.

Fight Aging! · 19:40

№03 / 20 · Lifespan.io

Montana’s Right-to-Try Law Enters a New Phase

Montana’s first experimental treatment review board has brought three longevity heavyweights into the state’s effort to expand access to experimental therapies. How much regulation is too much? Many people in the longevity field will tell you that regulation is holding it back.

Lifespan.io · 16:24

№04 / 20 · Fight Aging!

Thymulin Produced by the Thymus Acts to Restrain Inflammation, But Declines with Age

The thymus is primarily noted as being the site of T cell maturation, essential to the supply of new T cells to maintain the adaptive immune system.

Fight Aging! · 11:22

№05 / 20 · Fight Aging!

Loss of Glymphatic Drainage of Cerebrospinal Fluid Correlates with Alzheimer's Disease Progression

A magnetic resonance imaging (MRI) approach known as diffusion tensor image analysis along the perivascular space (DTI-ALPS) can be used to measure the flow of cerebrospinal fluid leaving the brain via the glymphatic system, a network of vessels that parallels blood vessels…

Fight Aging! · 11:11

№06 / 20 · Nature Aging

Modernizing cognitive assessment in Alzheimer’s disease

Blood biomarkers enable early detection of Alzheimer’s disease pathology, but clinical pathways wait to detect late-stage cognitive impairment. Digital cognitive assessments that target Alzheimer’s-disease-vulnerable systems can detect earlier functional change and strengthen plasma-biomarker prognosis.

Nature Aging · 01:00

№07 / 20 · Nature Aging

Author Correction: Skin chronological aging drives age-related bone loss via secretion of cystatin-A

Nature Aging · 01:00

№08 / 20 · Nature Ageing

Probiotic effects on brain health are both transient and sustained for several weeks after discontinuation: a randomised controlled trial

Nature Ageing · 01:00

№09 / 20 · Nature Ageing

Local catecholamine catabolism blunts lipolysis in ageing adipose tissue

Nature Ageing · 01:00

№10 / 20 · Nature Ageing

Targeted modulation of phosphate and lipid metabolism reduces ligament mineralization in col9a1b deficient zebrafish

Nature Ageing · 01:00

№11 / 20 · Nature Ageing

Anti-IL-11 treatment improves ovarian function by reducing matrix stiffness

Nature Ageing · 01:00

Also today · №12–20

№12 · GeroScience · 01:00

Joint effects of social determinants of health on NAFLD mortality: the mediating role of phenotypic age acceleration

Although individual social determinants of health (SDoH) are known to influence non-alcoholic fatty liver disease (NAFLD)…
№13 · GeroScience · 01:00

Late-night dinner, skipping breakfast, and the risk of dementia in Japan: the LIFE Study

Evidence on meal timing and dementia is limited. We examined late-night dinner and skipping breakfast in…
№14 · GeroScience · 01:00

Age- and sex- related patterns in hematobiochemical and anthropometric parameters of Macaca monkeys

Nonhuman primates are widely used in preclinical biomedical research, with hematobiochemical values serving as key clinical…
№15 · News-Medical · 20:13

THC and CBD combination rapidly reduces advanced dementia agitation

A combination of CBD and THC rapidly and significantly reduces agitation in hospice-eligible people with dementia…
№16 · News-Medical · 19:56

Blocking the Axl receptor may offer a new way to promote bone formation

Osteoporosis is one of the most common age-related bone diseases, affecting millions of people worldwide and…
№17 · News-Medical · 19:24

TGen joins Collaborative Research Network for Parkinson's disease research

The Translational Genomics Research Institute (TGen), part of City of Hope, today announced it has been…
№18 · News-Medical · 15:16

Heatwave exposure associated with accelerated biological aging in middle-aged and older adults

As global climate change intensifies, heatwaves are becoming more frequent, longer, and more severe, emerging as…
№19 · Aging Cell · 09:39

Metabolic Signatures of Aging and Gametogenesis in Hydra oligactis

Hydra oligactis undergoes cold-induced sexual differentiation and aging, culminating in death. GC–MS-based metabolite profiling revealed signatures…
№20 · News-Medical · 08:06

Can Alzheimer's genes predict who becomes a SuperAger?

A study on SuperAgers shows exceptional memory isn't solely due to lower Alzheimer's genetic risk, highlighting…

Edition №23 complete

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Aggregated longevity news, not medical advice. Consult a clinician before acting on anything you read here.