The daily longevity edition
№18
Today’s lead
More Autophagy Reduces Toxin-Induced Kidney Failure in Mice
Autophagy, which increases in younger mice under toxic stress, does not increase in older mice and leaves them susceptible to acute kidney injury (AKI). Increasing autophagic flux by targeting a key molecule, transcription factor EB (TFEB), alleviates some of this damage.
Lifespan.io · 21:28
№02 / 17 · Fight Aging!
Gut Microbiome Composition Correlates with Epigenetic Clock Results
The gut microbiome changes with age in ways the provoke chronic inflammation and tissue dysfunction. Animal studies demonstrate that restoring a youthful gut microbiome to old individuals extends life and improves health.
Fight Aging! · 19:22
№03 / 17 · Fight Aging!
A View of Aging Centered Around the Role of Karyopherins and Nuclear Transport
The biochemistry of aging is enormously complex, and it is very hard to pick apart which changes are definitively cause versus effect, and which changes are definitively more important than others.
Fight Aging! · 11:22
№04 / 17 · Fight Aging!
Reviewing Age-Related Changes in Microglia
Microglia are innate immune cells resident in the brain, analogous to macrophages elsewhere in the body. Like macrophages, microglia are deeply involved in tissue maintenance as well as defense against pathogens and destruction of potentially cancerous, malfunctioning cells.
Fight Aging! · 11:11
№05 / 17 · The Guardian
The Guardian view on Europe’s demographic crisis: the young must not be left to deal with the consequences | Editorial
A new Brussels study highlights the pace at which EU countries are ageing. A more informed public debate is overdue Europe is ageing at pace as birthrates fall and people live longer.
The Guardian · 18:22
№06 / 17 · News-Medical
Persistent financial hardship accelerates age-related cognitive decline
Persistent financial hardship accelerates age-related cognitive decline, according to a new study led by University College London (UCL) researchers.
News-Medical · 04:06
№07 / 17 · Nature Ageing
The cardiac 4D nucleome: nuclear and chromatin dynamics across development, disease and ageing
Nature Ageing · 01:00
№08 / 17 · News-Medical
Targeting acid ceramidase could improve healthy aging and longevity
Our population is aging. The United Nations reports that by 2050, the number of people over the age of 85 on our planet is set to triple.
News-Medical · 03:31
№09 / 17 · Blue Zones
The Art of The Slow Morning: How Early Risers In The Blue Zones Start The Day
Science confirms that morning routines rooted in self-care are a recipe for well-balanced nervous systems and better-regulated cortisol levels.
Blue Zones · 16:49
№10 / 17 · GeroScience
Interstitial fluid rejuvenation through young-donor plasma exchange in cognitively impaired patients: a pilot safety and feasibility study
Heterochronic parabiosis improves physiological and cognitive function in aging rodents; these benefits appear to be derived from the removal of aged blood plasma components and the addition of younger ones.
GeroScience · 01:00
№11 / 17 · GeroScience
Micronutrients and omega-3 PUFAs to promote healthy ageing: informing a physiology-based complementation strategy
Global population ageing is increasing the burden of chronic disease, functional decline, and loss of independence. For most organs, decline in function starts during the 5th decade of life. Micronutrient (MN) insufficiencies/deficiencies are common and may accelerate biological ageing.
GeroScience · 01:00
Also today · №12–17
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№12 · Brad Stanfield · 17:10
"Lie to Your Doctor" ▶
🩺 Get your personalized health plan: 📄 Full write-up & all the studies from this video…
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№13 · ScienceAlert · 21:00
One Diet Helped Aging Mice Lose Fat While Preserving Muscle
"Seems to redirect a specific hormonal signal.” ScienceAlert stories are written, fact-checked, and edited by humans…
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№14 · News-Medical · 20:49
Study reveals dynamic remodeling of genome architecture during brain aging
Researchers have discovered that the human brain undergoes widespread age-related changes in genome regulation beginning in…
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№15 · Physionic · 13:00
The Ultimate Peptide Stack? Gain Muscle, Lose Fat! ▶
*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: *EMAIL LIST* 1-2 Weekly Email of…
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№16 · News-Medical · 05:47
Spermidine boosts key cellular processes linked to aging in early research
This review finds that spermidine supports autophagy, mitochondrial function, and healthspan in experimental models, while observational…
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№17 · News-Medical · 05:16
Thymulin curbs age-related inflammation and slows breast tumors in mice
Thymulin reduced age-associated inflammatory myeloid cells and slowed breast-tumor growth in aged mice by suppressing NF-κB…
Edition №18 complete
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Aggregated longevity news, not medical advice. Consult a clinician before acting on anything you read here.