Quantifying the Risk of Alzheimer's Disease Associated with High Levels of p-tau217 in Blood

The first predictive blood tests for future risk of Alzheimer's disease were developed in recent years based on correlations between marker proteins in the blood and disease risk derived from large epidemiological studies.

Fight Aging! · 19:22

№02 / 22 · Lifespan.io

The Progress and Future of Biological Aging Clocks

A recent review discusses the development of biological aging clocks, their capabilities and limitations, the discoveries they enabled, and possible future developments in this area [1].

Lifespan.io · 17:52

№03 / 22 · Peter Attia

Should you choose organic food?

From pesticides and GMOs to nutrient content and antibiotic exposure, we investigate the case for choosing organic food over conventional.

Peter Attia · 02:00

№04 / 22 · Fight Aging!

How to Go About Measuring Health in Aging is its Own Sizable Debate

Health is like art; one knows it if one sees it. But that isn't good enough for the development of therapies. Health must be pinned down and actually measured.

Fight Aging! · 11:22

№05 / 22 · Fight Aging!

CMLase Enzyme Developed to Break Down CML Advanced Glycation Endproducts

Advanced glycation endproducts (AGEs) are a broad class of sugar-modified molecules that have harmful effects in the body.

Fight Aging! · 11:11

№06 / 22 · ScienceDaily Aging

Colorectal cancer warning signs younger adults should never ignore

Colorectal cancer is now the leading cause of cancer death among people under 50, and cases in younger adults continue to rise. Warning signs can include persistent bowel changes, recurring rectal bleeding, dark or narrow stools, unexplained weight loss, and fatigue.

ScienceDaily Aging · 13:47

№07 / 22 · ScienceDaily Aging

Lab-grown mini brains may predict which Alzheimer’s treatments will work

Miniature brain models grown from patients’ cells revealed striking differences in how Alzheimer’s-related tissue responds to an antidepressant. The organoids and the particles they release could eventually guide more personalized treatments and provide new clues for diagnosing the disease.

ScienceDaily Aging · 13:34

№08 / 22 · Aging Cell

The Divergent Effects of Nicotinamide Riboside and High‐Intensity Exercise Training on Skeletal Muscle Epigenetic Aging

This study investigated the effects of nicotinamide riboside supplementation and high-intensity interval training on skeletal muscle epigenetic aging.

Aging Cell · 04:10

№09 / 22 · News-Medical

Senolytic drugs rejuvenate blood stem cells in sickle cell disease

Sickle cell disease causes premature aging of blood stem cells, which scientists may be able to address with a special class of drugs, according to a new study from St. Jude Children's Research Hospital.

News-Medical · 04:00

№10 / 22 · News-Medical

Frequent TV watching links to higher white matter lesion volume

ARIC researchers linked self-reported TV watching and occupational sitting in midlife with brain MRI measures obtained roughly 24 years later in 1,712 adults without dementia.

News-Medical · 01:55

№11 / 22 · GeroScience

The PERK paradox in aging: how ER stress shapes senescence and neurodegeneration

Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) are now recognized as integral components of the proteostasis network that preserves cellular and tissue function across the lifespan.

GeroScience · 01:00

Also today · №12–22

№12 · GeroScience · 01:00

VCD-induced estropause fails to enhance responsiveness to 17α-estradiol in adult female mice

17α-estradiol (17α-E2) extends median lifespan and improves metabolic homeostasis in male mice through estrogen receptor α…
№13 · GeroScience · 01:00

Olfactory dysfunction is associated with gait impairment in older adults: evidence for a shared amygdala substrate

Olfactory dysfunction and gait impairment are common in older adults and may reflect shared neural vulnerability…
№14 · GeroScience · 01:00

Hypertension-associated DNA methylation signatures and multi-generational epigenetic clocks in Korean adults

Hypertension is a hallmark of vascular aging; however, the epigenetic link between biological aging and blood…
№15 · Aging Cell · 20:26

Ammonia Metabolism in the Aging Liver: Emerging Mechanistic Insights

Liver aging may weaken ammonia-detoxification reserve by disrupting mitochondrial ureagenesis, GS-mediated scavenging, glutamine metabolism, and metabolic…
№16 · Aging Cell · 20:25

Muscle Mitochondrial Oxidative Capacity and Cognitive Decline Over up to a Decade: Sex Differences

Skeletal muscle mitochondrial oxidative capacity is linked to cognition and predicts cognitive decline primarily in men…
№17 · Aging Cell · 20:24

Mechanistic Study of Platelet Membrane‐Coated Resveratrol Nanosystem in Mitochondrial Dysfunction and Endothelial Senescence During Atherosclerotic Lesion Development via FOXM1 Activation

Schematic diagram of the mechanism by which PM@RSV NPs alleviate AS via FOXM1 activation. Atherosclerosis (AS)…
№18 · Aging Cell · 20:23

Down‐Regulation of TFEB With Defective Autophagy in the Susceptibility of Aging Kidneys to Septic Acute Kidney Injury

Aging is associated with impaired TFEB-dependent autophagy in renal proximal tubular epithelial cells, leading to increased…
№19 · ScienceAlert · 13:00

42 Studies Confirm: Air Pollution Is Linked to Higher Parkinson's Risk

ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a…
№20 · ScienceAlert · 11:00

Ultimate Limit of The Human Lifespan May Be Identified, Study Suggests

ScienceAlert stories are written, fact-checked, and edited by humans, never generated by AI. Don't miss a…
№21 · Aging Cell · 11:01

Issue Information

Aging Cell, Volume 25, Issue 8, August 2026.
№22 · News-Medical · 05:28

Five epigenetic clocks reveal shared and distinct signals of aging

Researchers linked five epigenetic clocks to distinct blood gene-expression patterns and biological pathways in 3,227 Health…

Edition №17 complete

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