Early-life sugar rationing, brain aging, and long-term neurodegenerative and psychiatric health outcomes: a population-based natural experiment study

npj Aging · 01:00

№02 / 19 · Fight Aging!

The Aging Immune System Disrupts Maintenance of Bone Tissue

As for all tissues, bone derives its structural properties from the composition and structure of its extracellular matrix. This matrix constantly undergoes dynamic modification: osteoclast cells break down the matrix, while osteoblast cells build it up.

Fight Aging! · 19:11

№03 / 19 · Lifespan.io

Regular Training Erases Parts of Muscle Aging Signature

A new study suggests that regular planned exercise, not just being generally active, protects against certain aspects of muscle aging [1]. With age, skeletal muscles lose strength, metabolic flexibility, and mitochondrial capacity.

Lifespan.io · 16:54

№04 / 19 · Fight Aging!

TFAM and Mitochondrial Dysfunction in Aging

Twenty years ago or so, researchers were investigating the possibility of building therapies based on upregulation of TFAM expression to improve mitochondrial function in aged tissues.

Fight Aging! · 11:22

№05 / 19 · Fight Aging!

Mitochondrial Dysfunction in Parkinson's Disease is Complicated

Like many age-related conditions, Parkinson's disease is associated with uncommon mutations and genetic variants that increase its likelihood, severity, and pace of progression.

Fight Aging! · 11:11

№06 / 19 · Nature Aging

Senescent cells cluster CTCF on nuclear speckles to instruct an alternative splicing program

Palikyras and colleagues investigate chromatin reorganization upon senescence induction, reporting that components of nuclear speckles coordinate chromatin rewiring and a senescence-associated splicing program. Interventions countering this reorganization delay senescence entry.

Nature Aging · 01:00

№07 / 19 · ScienceDaily Aging

Watching too much TV in midlife may shrink the brain

Watching television very often in midlife may be linked to troubling brain changes decades later.

ScienceDaily Aging · 14:29

№08 / 19 · Nature Ageing

Thymulin restrains age-associated myeloid inflammation and enhances cancer immunotherapy

Nature Ageing · 01:00

№09 / 19 · News-Medical

Dementia addiction and psychiatric disorders show distinct patterns of accelerated brain aging

People with dementia, mild cognitive impairment, alcohol addiction, or psychiatric disorders such as schizophrenia show increased brain aging, each in specific patterns within the brain, according to a study published July 21st in the open access journal PLOS Medicine by Shile Qi…

News-Medical · 03:39

№10 / 19 · GeroScience

A metabolomic clock of population ageing: cross-cohort validation and associations with frailty and cognitive function

Understanding the links between metabolism, ageing, and age-related phenotypes may clarify the role of ageing in disease onset and improve risk prediction.

GeroScience · 01:00

№11 / 19 · News-Medical

Peroxisome preservation extends lifespan and protects mitochondrial health in worms

A new research paper was published in Volume 18 of Aging on July 6, 2026, titled "Inhibition of peroxisomal protein PRX-11 promotes longevity in Caenorhabditis elegans via enhancements to mitochondria."

News-Medical · 17:32

Also today · №12–19

№12 · News-Medical · 14:47

Thymus hormone identified as key player in reversing age-related inflammation

Chronic, low-grade inflammation in the body-a phenomenon known as "inflammaging" because it increases with age-has been…
№13 · Aging Cell · 08:00

Gut Metabolism Links Precision Nutrition, Exercise, and Healthspan in Drosophila melanogaster

This study reveals that precision nutrition, exercise, and gut microbiota pathways synergistically regulate host metabolism, redox…
№14 · Aging Cell · 08:00

Anatomical Society Research Studentships 2026/27

Aging Cell, Volume 25, Issue 7, July 2026.
№15 · npj Aging · 01:00

Intermittent chloroquine treatment extends lifespan and prevents mammary hyperplasia in female rats while reducing serum ldl and igfbp3 levels

Intermittent chloroquine treatment extends lifespan and prevents mammary hyperplasia in female rats while reducing serum ldl…
№16 · npj Aging · 01:00

How epigenetic clocks tick: unpacking the black box by deciphering biological pathways and transcriptomic signatures of accelerated aging

How epigenetic clocks tick: unpacking the black box by deciphering biological pathways and transcriptomic signatures of…
№17 · npj Aging · 01:00

Geroprotective insights into the natural metabolite spermidine in aging and age-related diseases

Geroprotective insights into the natural metabolite spermidine in aging and age-related diseases
№18 · Brad Stanfield · 17:48

The 120/80 Blood Pressure Target Is Wrong ▶

🩺 Get your personalized health plan: 📄 Full write-up & all the studies from this video…
№19 · Physionic · 13:00

14 Cheese Studies: A Surprising Relationship with Death ▶

*JOIN THE PHYSIONIC INSIDERS [PREMIUM CONTENT]* Join the Physionic Insiders: *EMAIL LIST* 1-2 Weekly Email of…

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Aggregated longevity news, not medical advice. Consult a clinician before acting on anything you read here.