Exosomes From Stem Cells Fight Liver Disease in Mice

Sarcopenia is the name given to later, more severe stages of the characteristic loss of muscle mass and strength that takes place with age. The loss is universal, ultimately leading to physical frailty.

The research community regularly produces quite fascinating data regarding the ways in which diet influences health. Take this paper, for example.

Microglia are innate immune cells of the brain, analogous to macrophages elsewhere in the body. Both cell types are deeply involved in the intricate processes of tissue maintenance and regeneration.

A large multicenter proteomics study identified blood biomarkers that distinguish Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, supporting biomarker-based differential diagnosis of neurodegenerative diseases.

This Perspective reviews TERT’s canonical telomere-maintenance and noncanonical regulatory roles in aging and outlines an evidence-based framework for evaluating TERT- and telomere-directed geroprotective strategies.

Researchers have uncovered a surprising culprit behind sleep loss in Alzheimer’s disease: the brain’s own immune cells. In mice with amyloid plaques, overactive microglia triggered inflammation that kept the brain from getting enough deep, restorative sleep.

"These are the tools to give you the 80/20 approach to engineer a reasonably safe environment from a pollution standpoint, without becoming a lifestyle devoid of any sanity.” —Peter Attia

Unsupervised serious video games on the SmartMe&You home telemonitoring platform may enable the assessment of cognitive fluctuations in older individuals, with or without cognitive deficits.

Scientists have redesigned zinc oxide particles to create a mineral sunscreen that protects against ultraviolet radiation without leaving such a noticeable white cast.

Filtered coffee consumption was associated with slower biological aging, while instant coffee was linked to faster aging in UK Biobank participants. The cross-sectional findings do not prove causation, but they suggest that brewing method may influence coffee’s relationship with aging biomarkers.